• Eat the most colorful fresh fruit and vegetables, which may contain chemopreventive agents (vitamins, minerals and fiber). Cruciferous vegetables such as broccoli and Brussel's sprouts are especially important. • Bran (oat or wheat) has a role in high fiber diets but the results are uncertain. Recent studies show that fiber probably plays a role in colon cancer prevention. • Wheat bran supplements may help inhibit polyp formation, but this has to be confirmed. It is possible that fiber in natural foods (fruits and vegetables) is better for cancer prevention.